Promising Start-up Domains

Written By bill haines

Start-up incubator Y-Combinator just published its 2024 wish list. Termed their “Request for Start-ups”, the list enumerates the areas that the group’s partners are most eager to support- areas where they see great promise.

While this is not the only wish list around, it’s a useful look at domains where some see significant potential. Not surprisingly, AI features prominently on the list, but there are also some interesting call outs like: “better enterprise glue”, “developer tools inspired by existing internal tools”, and “commercial open source companies”.

  • Applying Machine Learning To Robotics

  • Using Machine Learning To Simulate The Physical World

  • New Defense Technology

  • Bring Manufacturing Back To America

  • New Space Companies

  • Climate Tech

  • Commercial Open Source Companies

  • Spatial Computing

  • New Enterprise Resource Planning Software

  • Developer Tools Inspired By Existing Internal Tools

  • Explainable A.I.

  • L.L.Ms For Manual Back Office Processes In Legacy Enterprises

  • A.I. To Build Enterprise Software

  • Stablecoin Finance

  • A Way To End Cancer

  • Foundation Models For Biological Systems

  • The Managed Service Organization Model For Healthcare

  • Eliminating Middlemen In Healthcare

  • Better Enterprise Glue

  • Small Fine Tuned Models As An Alternative To Giant Generic Ones

Y-Combinator provides an explanation of each category on their site.

Bill Haines, Partner

bill haines
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